Publications/業績
Original papers/英語原著論文（査読有）
1. Tamaru T, Kobayakawa K, Saiwai H, Konno D, Kijima K, Yoshizaki S, Hata K, Iura H, Ono G, Haruta Y, Kitade K, Iida KI, Kawaguchi KI, Matsumoto Y, Kubota K, Maeda T, Okada S, Nakashima Y.
Glial scar survives until the chronic phase by recruiting scar-forming astrocytes after spinal cord injury. Exp Neurol. 2022 Nov 3;114264. doi: 10.1016/j.expneurol.2022.114264.
2. Haruta Y, Kobayakawa K, Saiwai H, Hata K, Tamaru T, Iura H, Ono G, Kitade K, Kijima K, Iida K, Kawaguchi K, Matsumoto Y, Kubota K, Maeda T, Konno DJ, Okada S, Nakashima Y.
Zinc chelator treatment in crush syndrome model mice attenuates ischemia-reperfusion-induced muscle injury due to suppressing of neutrophil infiltration. Sci Rep. 2022 Sep 16;12(1):15580. doi: 10.1038/s41598-022-19903-0.
3. Yoshizaki S, Tamaru T, Hara M, Kijima K, Tanaka M, Konno DJ, Matsumoto Y, Nakashima Y, Okada S.
Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway. J Neuroinflammation. 2021 Jan 6;18(1):12. doi: 10.1186/s12974-020-02059-x.
4. Higashi K, Maeda K, Miyata K, Yoshimura S, Yamada K, Konno D, Tachibana T, Saito K.
Carbohydrate 3′-sialyllactose as a novel target for theranostics in pancreatic ductal adenocarcinoma. Tumor Biology. 2020 Oct;1–9. DOI: 10.1177/1010428320965279.
5. Gotoh N, Saito Y, Hata S, Saito H, Ojima D, Murayama C, Shigeta M, Abe T, Konno D, Matsuzaki F, Suzuki T, Yamamoto T.
Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice. J Biol Chem. 2020 Jul 10;295(28):9650-9662. doi: 10.1074/jbc.RA119.012386.
6. Xu L, Ihara KI, Yoshimura S, Konno D, Tachibana A, Nakanishi T, Tachibana T.
Generation of the Rat Monoclonal Antibody Against the Extracellular Domain of Human CD63 by DNA Immunization. Monoclon Antib Immunodiagn Immunother. 2020 Jun;39(3):74-76. doi: 10.1089/mab.2020.0007.
7. Kikkawa T, Sakayori N, Yuuki H, Katsuyama Y, Matsuzaki F, Konno D, Abe T, Kiyonari H, Osumi N.
Dmrt genes participate in the development of Cajal-Retzius cells derived from the cortical hem in the telencephalon. Dev Dyn. 2020 Jun;249(6):698-710. doi: 10.1002/dvdy.156.
8. Fujita I, Shitamukai A, Kusumoto F, Mase S, Suetsugu T, Omori A, Kato K, Abe T, Shioi G, Konno D, Matsuzaki F.
Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development. Nature Cell Biol. 2020 Jan;22(1):26-37. doi: 10.1038/s41556-019-0436-9
9. Yoshizaki S, Yokota K, Kubota K, Saito T, Tanaka M, Konno DJ, Maeda T, Matsumoto Y, Nakashima Y, Okada S.
The beneficial aspects of spasticity in relation to ambulatory ability in mice with spinal cord injury. Spinal Cord. 2019 Dec 10. doi: 10.1038/s41393-019-0395-9.
10. Konno D*, Kishida C, Maehara K, Ohkawa Y, Kiyonari H, Okada S, Matsuzaki F*.
Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes. Development. 2019 Aug 13;146(15). pii: dev174243. doi: 10.1242/dev.174243.
*Co-corresponding author.
11. Yoshizaki S, Kijima K, Hara M, Saito T, Tamaru T, Tanaka M, Konno D, Nakashima Y, Okada S.
Tranexamic acid reduces heme cytotoxicity via the TLR4/TNF axis and ameliorates functional recovery after spinal cord injury. J Neuroinflammation. 2019 Jul 29;16(1):160. doi: 10.1186/s12974-019-1536-y.
12. Kijima K, Kubota K, Hara M, Kobayakawa K, Yokota K, Saito T, Yoshizaki S, Maeda T, Konno D, Matsumoto Y, Nakashima Y, Okada S.
The acute phase serum zinc concentration is a reliable biomarker for predicting the functional outcome after spinal cord injury. EBioMedicine. 2019 Mar;41:659-669. doi: 10.1016/j.ebiom.2019.03.003.
13. Saadaoui M, Konno D, Loulier K, Goiame R, Jadhav V, Mapelli M, Matsuzaki F, Morin X.
Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3. EMBO Rep. 2017 Sep;18(9):1509-1520. doi: 10.15252/embr.201643048.
14. Inoue M, Tabata H, Iwai R, Konno D, Komabayashi-Suzuki M, Yamamoto S, Nanahara Y, Iwanari H, Mochizuki Y, Hamakubo T, Matsuzaki F, Nagata K, Mizutani K.
Prdm16 is critical for progression of multipolar phase during neural differentiation of developing neocortex. Development. 2016 Dec 19. pii: dev.136382.
15. Okamoto M, Miyata T, Konno D, Ueda HR, Kasukawa T, Hashimoto M, Matsuzaki F, Kawaguchi A.
Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells. Nature Commun. 2016 Apr 20;7:11349. doi: 10.1038/ncomms11349.
16. Kato K, Konno D, Berry M, Matsuzaki F, Logan A, Hidalgo A.
Prox1 Inhibits Proliferation and Is Required for Differentiation of the Oligodendrocyte Cell Lineage in the Mouse. PLoS One 2015 Dec 28;10(12):e0145334.
17. Konno D, Kasukawa T, Hashimoto K, Itoh T, Suetsugu T, Miura I, Wakana S, Carninci P, Matsuzaki F.
STAP cells are derived from ES cells. Nature. 2015 Sep 24;525(7570):E4-5.
18. Yamamoto H, Mandai K, Konno D, Maruo T, Matsuzaki F, Takai Y.
Impairment of radial glial scaffold-dependent neuronal migration and formation of double cortex by genetic ablation of afadin. Brain Res. 2015 Sep 16;1620:139-52.
19. Harada A, Maehara K, Sato Y, Konno D, Tachibana T, Kimura H, Ohkawa Y.
Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle. Nucleic Acids Res. 2015 Jan;43(2):775-86.
20. Shimozawa T, Yamagata K, Kondo T, Hayashi S, Shitamukai A, Konno D, Matsuzaki F, Takayama J, Onami S, Nakayama H, Kosugi Y, Watanabe TM, Fujita K, Mimori-Kiyosue Y.
Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3399-404.
21. Konno D*, Iwashita M, Satoh Y, Momiyama A, Abe T, Kiyonari H, Matsuzaki F*.
The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex. PLoS One. 2012;7(10):e46577. *Co-corresponding author.
22. Harada A, Okada S, Konno D, Odawara J, Yoshimi T, Yoshimura S, Kumamaru H, Saiwai H, Tsubota T, Kurumizaka H, Akashi K, Tachibana T, Imbalzano AN, Ohkawa Y.
Chd2 interacts with H3.3 to determine myogenic cell fate. EMBO J. 2012 Jun 29;31(13):2994-3007.
23. Shitamukai A, Konno D, Matsuzaki F.
Oblique radial glial divisions in the developing mouse neocortex induce self-renewing progenitors outside the germinal zone that resemble primate outer subventricular zone progenitors. J Neurosci. 2011 Mar 9;31(10):3683-95.
24. Yokoyama C, Katoh-Fukui Y, Morohashi K, Konno D, Azuma M, Tachibana T.
Production and characterization of monoclonal antibodies to mouse germ cells. Hybridoma (Larchmt). 2010 Feb;29(1):53-7.
25. Shioi G, Konno D, Shitamukai A, Matsuzaki F.
Structural basis for self-renewal of neural progenitors in cortical neurogenesis. Cereb Cortex. 2009 Jul;19 Suppl 1:i55-61. Epub 2009 Apr 10.
26. Konno D, Shioi G, Shitamukai A, Mori A, Kiyonari H, Miyata T, Matsuzaki F.
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nature Cell Biol. 2008 Jan;10(1):93-101. Epub 2007 Dec 16.
27. Ando K, Nagano T, Nakamura A, Konno D, Yagi H, Sato M.
Expression and characterization of disulfide bond use of oligomerized A2-Pancortins: extracellular matrix constituents in the developing brain. Neuroscience. 2005;133(4):947-57.
28. Hori K, Yasuda H, Konno D, Maruoka H, Tsumoto T, Sobue K.
NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signaling. J Neurosci. 2005 Mar 9;25(10):2670-81.
29. Maruoka H, Konno D, Hori K, Sobue K.
Collaboration of PSD-Zip70 with its binding partner, SPAR, in dendritic spine maturity. J Neurosci. 2005 Feb 9;25(6):1421-30.
30. Yagi H, Takamura Y, Yoneda T, Konno D, Akagi Y, Yoshida K, Sato M.
Vlgr1 knockout mice show audiogenic seizure susceptibility. J Neurochem. 2005 Jan;92(1):191-202.
31. Konno D, Yoshimura S, Hori K, Maruoka H, Sobue K.
Involvement of the phosphatidylinositol 3-kinase/rac1 and cdc42 pathways in radial migration of cortical neurons. J Biol. Chem. 2005 Feb 11;280(6):5082-8. Epub 2004 Nov 22.
32. Hori K, Konno D, Maruoka H, Sobue K.
MALS is a binding partner of IRSp53 at cell-cell contacts. FEBS Lett. 2003 Nov 6;554(1-2):30-4.
33. Usui S, Konno D, Hori K, Maruoka H, Okabe S, Fujikado T, Tano Y, Sobue K.
Synaptic targeting of PSD-Zip45 (Homer 1c) and its involvement in the synaptic accumulation of F-actin. J Biol. Chem. 2003 Mar 21;278(12):10619-28. Epub 2003 Jan 10.
34. Konno D, Ko JA, Usui S, Hori K, Maruoka H, Inui M, Fujikado T, Tano Y, Suzuki T, Tohyama K, Sobue K. The postsynaptic density and dendritic raft localization of PSD-Zip70, which contains an N-myristoylation sequence and leucine-zipper motifs. J Cell Sci. 2002 Dec 1;115(Pt 23):4695-706.
35. Okabe S, Urushido T, Konno D, Okado H, Sobue K.
Rapid redistribution of the postsynaptic density protein PSD-Zip45 (Homer 1c) and its differential regulation by NMDA receptors and calcium channels. J Neurosci. 2001 Dec 15;21(24):9561-71.
36. Nagano T, Nakamura A, Konno D, Kurata M, Yagi H, Sato M.
A2-Pancortins (Pancortin-3 and -4) are the dominant pancortins during neocortical development. J Neurochem. 2000 Jul;75(1):1-8.Co
【その他の著作物】
2009年
“哺乳類神経前前駆細胞の自己複製および分化における分裂軸制御の役割”今野 大治郎、松崎 文雄 細胞工学 Vol.28 No.1 秀潤社（2009年1月）
2008年
第４章 ”非対称分裂による神経細胞の誕生” 今野 大治郎、松崎 文雄 シリーズ脳科学第４巻 「脳の発生と発達」岡本仁編集、東京大学出版会（2008年9月）
2003年
第２編−１ “シナプス後肥厚部PSDの分子構築と機能制御” 今野 大治郎、祖父江憲治
「動くシナプスと神経ネットワーク」、塩坂貞夫編集、金芳堂（2003年9月）
2002年
第3章 “細胞骨格タンパク質と脳機能” 祖父江憲治、今野大治郎、堀啓
シリーズバイオサイエンスの新世紀 「感覚器官と脳内情報処理」御子柴克彦、清水孝雄編集、日本生化学会編集（2002年9月）
【新聞掲載等】
2019年12月24日
理化学研究所プレスリリース「神経幹細胞の再生能を発見－細胞の「形」の柔軟性が脳の拡大に果たす役割－」
https://www.riken.jp/press/2019/20191224_1/index.html
2011年7月4日
理化学研究所プレスリリース「脳進化をもたらした神経幹細胞の新たな分裂様式」
http://www.cdb.riken.jp/jp/04_news/articles/11/110704_progenitors.html
2008年1月8日
理化学研究所プレスリリース「LGNが神経上皮細胞の自己複製能を維持している」
http://www.cdb.riken.jp/jp/04_news/articles/080108_neurorientation.html